[NovoPro 한국공식대리점] Exatecan Monoclonal Antibody 제품소개

[NovoPro] Product

[NovoPro] Exatecan Monoclonal Antibody

Product Information:

• Product Name: Exatecan Monoclonal Antibody
• Cat#: 176731
• Size: 100μg, 200μg
• Description: Product has been tested in direct ELISA
• Clonality: Monoclonal
• Tested applications: ELISA
• Species reactivity: Chemical
• Isotype: Mouse IgG2b.k
• Formulation: PBS(pH7.4), lyophilized. Reconstitution: Adding sterile water, prepare a stock solution of 2.0 mg/ml.
• Preparation: Exatecan conjugated with OVA. Protein G affinity purified
• Storage instructions: Store at -20℃. Avoid freeze / thaw cycles.
• Applications: ELISA: 1:5,000-1:20,000
• Background: Exatecan (Exa) is a very potent inhibitor of topoisomerase I and anticancer agent. It has been intensively studied as a single agent, a large macromolecular conjugate and as the payload component of antigen-dependent antibody–drug conjugates. Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL).